Scientists have claimed the coronavirus can enter the body through eyes.
This is after researchers found out the mechanism for how the virus works, as the coronavirus has a protein used to bind to cells. This virsus only attaches itself to ACE-2 receptors, the gateway cells. These receptors are mostly found in respiratory tract and lungs – and now the Johns Hopkins University School of Medicine have found these receptors in the eyes as well, giving the initiative to protect them from vulnerability.
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The virus could begin infiltrating cells from the eyes.point 161 | Conjunctivitis – an inflammation of the eye which causes it to become red and infected – may now be explained from some patients suffering it.point 291 |
“Not only could the virus enter the body through the eyes, but tears may serve as a spread of infection”, scientists said.point 113 | Led by Lingli Zhou of the Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, the team carried out extensive research, taking eye samples from the COVID-19 corpses for discovering ACE2 (angiotensin-converting enzyme 2) “.point 338 |
” It’s suggested that someone with more ACE-2 receptors may be more susceptible to a large viral load – first infectious dose of a virus – entering their bloodstream.point 162 | 1
The team also said that they have looked for TMPRSS2, an enzyme that “helps viral entry following binding of the viral spike protein to ACE2.point 402 |
ACE2 and TMPRSS2 must both be present in the same cell for the virus to effectively replicate.point 78 | All eye specimens expressed ACE-2 in the tissue that lines the inside of the eyelids, called conjunctiva, the clear outer layer of the eye, called the cornea, and the limbus, which is the border between the cornea and the white of the eye.point 275 |
”, citing the work procedure that they have made in the researching period.point 69 | 1
TMPRSS2 was also expressed, according to the pre-print paper on MedRxiv yet to be reviewed by other scientists.point 291 |
Dr Zhou and colleagues wrote: ‘Together, these results indicate that ocular surface cells including conjunctiva are susceptible to infection by SARS-CoV-2, and could therefore serve as a portal of entry as well as a reservoir for person-to-person transmission of this virus.point 240 |
’ This will embetter the understanding we have on the virus, if only by little.point 71 | 1
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